{"product_id":"reta-tik-glp3-10mg-vial","title":"Reta-Tik™ GLP3 Lyophilized Vial + Sterile Water","description":"\u003ch3\u003eAbout Reta-Tik™\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eTriple-Receptor Action · GLP-1 · GIP · Glucagon · Appetite Signaling · Energy Metabolism\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBEYOND A SINGLE TARGET. THREE METABOLIC PATHWAYS.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe triple-receptor concept behind \u003cstrong\u003eReta-Tik™\u003c\/strong\u003e brings together \u003cstrong\u003eGLP-1, GIP and glucagon receptor activation\u003c\/strong\u003e in a single investigational molecule. These pathways are involved in \u003cstrong\u003eappetite regulation, glucose control and energy metabolism\u003c\/strong\u003e, creating a distinct approach to metabolic science.\u003c\/p\u003e\u003ch3\u003eBeyond Dual-Receptor Signaling\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eTirzepatide activates GLP-1 and GIP receptors. The triple-receptor approach adds glucagon receptor activation.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThat third target is the defining difference. In preclinical studies, glucagon receptor activation contributed to \u003cstrong\u003eincreased energy expenditure\u003c\/strong\u003e, alongside reduced food intake associated with incretin receptor activation. \u003cstrong\u003eA broader mechanism does not, by itself, prove better clinical results.\u003c\/strong\u003e\u003c\/p\u003e\u003ch3\u003eClinical Data That Commands Attention\u003c\/h3\u003e\u003cp\u003eA \u003cstrong\u003e2023 phase 2 trial published in The New England Journal of Medicine\u003c\/strong\u003e, involving \u003cstrong\u003e338 adults with obesity or overweight and a weight-related condition\u003c\/strong\u003e, reported mean body-weight reductions in the \u003cstrong\u003e12 mg study group\u003c\/strong\u003e of:\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e17.5% at 24 weeks\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e24.2% at 48 weeks\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe corresponding placebo reductions were \u003cstrong\u003e1.6% and 2.1%\u003c\/strong\u003e. These percentages are study-group averages under controlled conditions, not guaranteed individual outcomes.\u003c\/p\u003e\u003cp\u003eFor context, the separate \u003cstrong\u003eSURMOUNT-1\u003c\/strong\u003e trial reported \u003cstrong\u003e22.5% mean body-weight reduction at 72 weeks\u003c\/strong\u003e in the tirzepatide \u003cstrong\u003e15 mg group\u003c\/strong\u003e, using an analysis estimating outcomes with continued treatment.\u003c\/p\u003e\u003ch3\u003eMore Than Appetite Alone\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eAppetite is one part of the metabolic picture.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe triple-receptor approach examines how \u003cstrong\u003efood intake, glucose regulation and energy expenditure\u003c\/strong\u003e interact. Its distinguishing feature is the combination of incretin signaling with glucagon receptor activity, rather than a focus on a single biological target.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eReta-Tik™. Triple-receptor science. A distinct metabolic approach.\u003c\/strong\u003e\u003c\/p\u003e\u003ch3\u003e\u003cbr\u003e\u003c\/h3\u003e\u003ch3\u003e\u003cbr\u003e\u003c\/h3\u003e","brand":"Peptik","offers":[{"title":"Vial \/ 10mg","offer_id":48963492053089,"sku":"1 vial 10 mg Reta-Tik + 1 vial 3 mL Bacteriostatic Water included","price":690.0,"currency_code":"AED","in_stock":true},{"title":"Pen (Ready to use) \/ 10mg","offer_id":48963492085857,"sku":"1 pen 10 mg Reta-Tik","price":990.0,"currency_code":"AED","in_stock":true},{"title":"Pen (Ready to use) \/ 20mg","offer_id":48963492118625,"sku":"1 Pen Reta-Tik 20 mg","price":1390.0,"currency_code":"AED","in_stock":true},{"title":"Vial \/ 40mg","offer_id":48963492151393,"sku":"1 vial 40 mg Reta-Tik + 1 vial 3 mL Bacteriostatic Water included","price":1390.0,"currency_code":"AED","in_stock":true},{"title":"Pen (Ready to use) \/ 40mg","offer_id":48963492184161,"sku":"1 pen 40 mg Reta-Tik","price":1990.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0625\/7413\/3345\/files\/reta-tik-glp3-10mg-vial_9afb3612-8116-4c11-b4d1-998cf4277143_a7d7a1d1-4071-43f5-86ac-1073440206ea.png?v=1790697135","url":"https:\/\/peptik.org\/products\/reta-tik-glp3-10mg-vial","provider":"PEPTIK","version":"1.0","type":"link"}